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anti-glua2-py 876  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc anti-glua2-py 876
    A single ECS but not chronic ECS increases the level of Tyr 876 -phosphorylated <t>GluA2</t> in the hippocampus. Immunoblot analysis for phosphorylation of GluA2 at Tyr 876 (Y 876 ) or 3Tyr (3Y: Tyr 869 , Tyr 873 , and Tyr 876 ) and total GluA2 expression in the hippocampal crude membrane (P2) fraction following a single ECS ( n = 5 rats per time point) (a–c) and chronic ECS ( n = 5 rats for 72 h time point and n = 6 rats per all other time points) (d–f). The ratio of the phosphorylated GluA2 band intensity over the β -actin band intensity (a-b, d-e) and the ratio of total GluA2 band intensity over the β -actin band intensity (c, f) were calculated per each time point and normalized to that of “no seizure” (NS) sham group. Data shown represent the mean band intensity ± SEM. (a–c) A single ECS increases the level of Tyr 876 -phosphorylated GluA2 at 96 h time point ((b) ∗ p < 0.05) but does not alter the level of 3Tyr-phosphorylated GluA2 and total GluA2. (d–f) Chronic ECS does not change Tyr-phosphorylation of GluA2 (d-e) and total GluA2 expression (f).
    Anti Glua2 Py 876, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti-glua2-py 876/product/Cell Signaling Technology Inc
    Average 90 stars, based on 1 article reviews
    anti-glua2-py 876 - by Bioz Stars, 2026-03
    90/100 stars

    Images

    1) Product Images from "Seizure-Induced Regulations of Amyloid- β , STEP 61 , and STEP 61 Substrates Involved in Hippocampal Synaptic Plasticity"

    Article Title: Seizure-Induced Regulations of Amyloid- β , STEP 61 , and STEP 61 Substrates Involved in Hippocampal Synaptic Plasticity

    Journal: Neural Plasticity

    doi: 10.1155/2016/2123748

    A single ECS but not chronic ECS increases the level of Tyr 876 -phosphorylated GluA2 in the hippocampus. Immunoblot analysis for phosphorylation of GluA2 at Tyr 876 (Y 876 ) or 3Tyr (3Y: Tyr 869 , Tyr 873 , and Tyr 876 ) and total GluA2 expression in the hippocampal crude membrane (P2) fraction following a single ECS ( n = 5 rats per time point) (a–c) and chronic ECS ( n = 5 rats for 72 h time point and n = 6 rats per all other time points) (d–f). The ratio of the phosphorylated GluA2 band intensity over the β -actin band intensity (a-b, d-e) and the ratio of total GluA2 band intensity over the β -actin band intensity (c, f) were calculated per each time point and normalized to that of “no seizure” (NS) sham group. Data shown represent the mean band intensity ± SEM. (a–c) A single ECS increases the level of Tyr 876 -phosphorylated GluA2 at 96 h time point ((b) ∗ p < 0.05) but does not alter the level of 3Tyr-phosphorylated GluA2 and total GluA2. (d–f) Chronic ECS does not change Tyr-phosphorylation of GluA2 (d-e) and total GluA2 expression (f).
    Figure Legend Snippet: A single ECS but not chronic ECS increases the level of Tyr 876 -phosphorylated GluA2 in the hippocampus. Immunoblot analysis for phosphorylation of GluA2 at Tyr 876 (Y 876 ) or 3Tyr (3Y: Tyr 869 , Tyr 873 , and Tyr 876 ) and total GluA2 expression in the hippocampal crude membrane (P2) fraction following a single ECS ( n = 5 rats per time point) (a–c) and chronic ECS ( n = 5 rats for 72 h time point and n = 6 rats per all other time points) (d–f). The ratio of the phosphorylated GluA2 band intensity over the β -actin band intensity (a-b, d-e) and the ratio of total GluA2 band intensity over the β -actin band intensity (c, f) were calculated per each time point and normalized to that of “no seizure” (NS) sham group. Data shown represent the mean band intensity ± SEM. (a–c) A single ECS increases the level of Tyr 876 -phosphorylated GluA2 at 96 h time point ((b) ∗ p < 0.05) but does not alter the level of 3Tyr-phosphorylated GluA2 and total GluA2. (d–f) Chronic ECS does not change Tyr-phosphorylation of GluA2 (d-e) and total GluA2 expression (f).

    Techniques Used: Western Blot, Expressing



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    anti-glua2-py 876  (Cell Signaling Technology Inc)
    90
    Cell Signaling Technology Inc anti-glua2-py 876
    A single ECS but not chronic ECS increases the level of Tyr 876 -phosphorylated <t>GluA2</t> in the hippocampus. Immunoblot analysis for phosphorylation of GluA2 at Tyr 876 (Y 876 ) or 3Tyr (3Y: Tyr 869 , Tyr 873 , and Tyr 876 ) and total GluA2 expression in the hippocampal crude membrane (P2) fraction following a single ECS ( n = 5 rats per time point) (a–c) and chronic ECS ( n = 5 rats for 72 h time point and n = 6 rats per all other time points) (d–f). The ratio of the phosphorylated GluA2 band intensity over the β -actin band intensity (a-b, d-e) and the ratio of total GluA2 band intensity over the β -actin band intensity (c, f) were calculated per each time point and normalized to that of “no seizure” (NS) sham group. Data shown represent the mean band intensity ± SEM. (a–c) A single ECS increases the level of Tyr 876 -phosphorylated GluA2 at 96 h time point ((b) ∗ p < 0.05) but does not alter the level of 3Tyr-phosphorylated GluA2 and total GluA2. (d–f) Chronic ECS does not change Tyr-phosphorylation of GluA2 (d-e) and total GluA2 expression (f).
    Anti Glua2 Py 876, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/anti-glua2-py 876/product/Cell Signaling Technology Inc
    Average 90 stars, based on 1 article reviews
    anti-glua2-py 876 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    A single ECS but not chronic ECS increases the level of Tyr 876 -phosphorylated GluA2 in the hippocampus. Immunoblot analysis for phosphorylation of GluA2 at Tyr 876 (Y 876 ) or 3Tyr (3Y: Tyr 869 , Tyr 873 , and Tyr 876 ) and total GluA2 expression in the hippocampal crude membrane (P2) fraction following a single ECS ( n = 5 rats per time point) (a–c) and chronic ECS ( n = 5 rats for 72 h time point and n = 6 rats per all other time points) (d–f). The ratio of the phosphorylated GluA2 band intensity over the β -actin band intensity (a-b, d-e) and the ratio of total GluA2 band intensity over the β -actin band intensity (c, f) were calculated per each time point and normalized to that of “no seizure” (NS) sham group. Data shown represent the mean band intensity ± SEM. (a–c) A single ECS increases the level of Tyr 876 -phosphorylated GluA2 at 96 h time point ((b) ∗ p < 0.05) but does not alter the level of 3Tyr-phosphorylated GluA2 and total GluA2. (d–f) Chronic ECS does not change Tyr-phosphorylation of GluA2 (d-e) and total GluA2 expression (f).

    Journal: Neural Plasticity

    Article Title: Seizure-Induced Regulations of Amyloid- β , STEP 61 , and STEP 61 Substrates Involved in Hippocampal Synaptic Plasticity

    doi: 10.1155/2016/2123748

    Figure Lengend Snippet: A single ECS but not chronic ECS increases the level of Tyr 876 -phosphorylated GluA2 in the hippocampus. Immunoblot analysis for phosphorylation of GluA2 at Tyr 876 (Y 876 ) or 3Tyr (3Y: Tyr 869 , Tyr 873 , and Tyr 876 ) and total GluA2 expression in the hippocampal crude membrane (P2) fraction following a single ECS ( n = 5 rats per time point) (a–c) and chronic ECS ( n = 5 rats for 72 h time point and n = 6 rats per all other time points) (d–f). The ratio of the phosphorylated GluA2 band intensity over the β -actin band intensity (a-b, d-e) and the ratio of total GluA2 band intensity over the β -actin band intensity (c, f) were calculated per each time point and normalized to that of “no seizure” (NS) sham group. Data shown represent the mean band intensity ± SEM. (a–c) A single ECS increases the level of Tyr 876 -phosphorylated GluA2 at 96 h time point ((b) ∗ p < 0.05) but does not alter the level of 3Tyr-phosphorylated GluA2 and total GluA2. (d–f) Chronic ECS does not change Tyr-phosphorylation of GluA2 (d-e) and total GluA2 expression (f).

    Article Snippet: Phosphorylation site specific antibodies used include anti-GluN2B-pTyr 1472 which recognizes phosphorylated Tyr-1472 of GluN2B (P1516-1472, PhosphoSolutions), anti-ERK1/2-pThr 202 /Tyr 204 which recognizes phosphorylated Thr 202 /Tyr 204 of ERK1 and Thr 185 /Tyr 187 of ERK2 (#9106, Cell Signaling), anti-GluA2-p3Y which recognizes phosphorylated Tyr 869 , Tyr 873 , and Tyr 876 (3Y) of GluA2 (#3921S, Cell Signaling), and anti-GluA2-pY 876 which recognizes phosphorylated Tyr 876 of GluA2 (#4027S, Cell Signaling).

    Techniques: Western Blot, Expressing